Medical Nanotechnology Research Group
The research activity of the Medical Nanotechnology group is focused on utilizing advanced nanomaterials and biotechnological approaches for impactful disease diagnostics and therapeutics. We integrate analytical chemistry, nanobiotechnology, and biomedical engineering to develop novel optical and electrochemical nanobiosensors as well as nanoscale therapeutic and theranostic platforms. The group extensively explores various nanomaterials including polymeric nanomaterials, two-dimensional nanomaterials, carbon nanodots, and metal nanoclusters for biomarker detection, imaging, and targeted therapy. Our work includes developing nanosystems capable of operating efficiently within the tumor microenvironment to ensure precise drug delivery and minimized side effects. A key focus of our research is designing nanostructures capable of multifunctional theranostics, combining diagnostics, imaging, and treatment into unified platforms. Our innovative research covers green synthesis methods, biosensing applications, and nanocarriers tailored for targeted drug delivery. This multidisciplinary effort harnesses chemistry, materials science, and biomedical engineering to push the frontiers of nanomedicine.
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Group Members
Faculty Member and Head of the Research Group
Zahra Mohammadpour
Assistant Professor
Ph.D. in Analytical Chemistry
Email: mohammadpour@acecr.ac.ir
Faculty Member
Fatemeh Molaabasi
Assistant Professor
Ph.D. in Analytical Chemistry
Email: molaabasi@acecr.ac.ir
Laboratory Specialist
Hosna Sadat Hoseini
M.Sc. in Chemical Engineering-Biotechnology
Selected Publications
[1] Ultra-efficient label-free cell death detection based on multifunctional colorimetric fluorescent in-situ silver nanocluster/graphene nanohybridzyme and its application in environmental biological samples and cellular imaging, Biosensors and Bioelectronics 291 (2026) 118020.
[2] Synthesis, characterization, and optimization of curcumin-loaded block copolymer nanoparticles for antibacterial applications, Chemical Engineering Journal 519 (2025) 165049.
[3] Optical and Electrochemical Biosensors for Detection of Pathogens Using Metal Nanoclusters: A Systematic Review, Biosensors 15 (2025) 460.
[4] Fluorescence and Circular Dichroism Dual-Mode Probe for Chiral Recognition of Tyrosine and Its Applications in Bioimaging, ACS Applied Materials & Interfaces 16 (2024) 48058-48072.
[5] Visible-light types I and II N-TiO2-based iron metalloporphyrin for efficient photodynamic therapy, Journal of the Iranian Chemical Society 21 (2024) 2753-2765.
[6] A review on polymeric nanocomposites for the electrochemical sensing of breast cancer biomarkers, Microchemical Journal 195 (2023) 109528.
[7] Immunomagnetic Isolation of HER2-Positive Breast Cancer Cells Using a Microfluidic Device, ACS Omega 8 (2023) 21745-21754.
[8] Synthesis of Fe-Doped Peroxidase Mimetic Nanozymes from Natural Hemoglobin for Colorimetric Biosensing and In Vitro Anticancer Effects, Biosensors 13 (2023) 583.
[9] A coumarin-based fluorescent chemosensor as a Sn indicator and a fluorescent cellular imaging agent, RSC Advances 13 (2023) 9811-9823.
[10] Multifunctional stimuli-responsive niosomal nanoparticles for co-delivery and co-administration of gene and bioactive compound: In vitro and in vivo studies, Chemical Engineering Journal 429 (2022) 132090.
[11] Smart stimuli-responsive implantable drug delivery systems for programmed and on-demand cancer treatment: An overview on the emerging materials, Chemical Engineering Journal 433 (2022) 134569.
